| Name | Death date | Birth location | Marriage date | Age at death |
| Irene Lorenz | August 09, 1978 | Dobersdorf, AU | WFT Est. 1937-1965 | 69 est. |
| Irene Malloy | | | | |
| Irene Meredith | | | | |
| Irene Meredith | | | | |
| Irene Salome Malloy | March 01, 1870 | South Bethlehem, Lower Saucon Twp, Northampton, Pa. | | 5 |
| Irene Stahl | | | | |
| Irene Thompson | | | | |
| Irene Unknown | | | | |
| Irene Victoria Gunkle | December 12, 1910 | Allentown, Salisbury Twp, Lehigh, Pa. | | 13 |
| Irene Ziemianski | | | | |
| Irvin Francis Paschall | Aft. 1924 | Buck, PA | | 44 est. |
| Irvin Franklin Bley | Aft. 1993 | Schuylkill, Pa. | | 84 est. |
| Isaac Boyer | September 25, 1875 | Northampton, Pa. | | 88 |
| Isaac Davis | | | Abt. 1756 | |
| Isaac Edward Webb | | | | |
| Isaac Fenstermacher | WFT Est. 1797-1886 | | | 1 est. |
| Isaac Leggett | | | August 16, 1828 | |
| Isaac Lynn | WFT Est. 1811-1900 | | | 1 est. |
| Isaac Martin 'Ike' Profitt | | | 1897 | |
| Isaac Miller | | | | |
| Isaac Muffly | 1825 | | | 27 est. |
| Isaac Newton Thomas | 1852 | | May 07, 1843 | 40 est. |
| Isaac Paschall | November 27, 1773 | Phil, PA | October 10, 1767 | 45 |
| Isaac Reich | September 10, 1856 | | | 35 |
| Isaac Roberts | | | March 04, 1740/41 | |
| Isaac Roberts | | | March 04, 1739/40 | |
| Isaac SNIDER | Aft. 1847 | | | ? |
| Isaac Stout | June 09, 1840 | Perkasie, Bucks, Pa. | | 90 |
| Isaac Transue | 1730 | Mutterstadt, Pfalz, Bavaria, Germany | | 1 est. |
| Isaac Wistar Morris | May 18, 1831 | Phil, PA | December 17, 1795 | 60 |
| Isabel Rebecca(C) BURDETT | January 26, 1934 | Jackson Co West Virginia | Bet. April 03 - 09, 1867 | 84 |
| Isabella 'Bell' (Isebell ) Stevenson | | PA res. Hickory Twnsp Mercer Co. 1860 | | |
| Isabella Frickleton | | | | |
| Isabella Johnston | August 05, 1912 | | | 82 |
| Isabella Johnston | | | | |
| Isabella Johnston | | | | |
| Isabella Lindsay | | | | |
| Isabella M. Kunkel | February 06, 1939 | Pa. | November 18, 1866 | 89 |
| Isabella Smith | December 31, 1876 | | | 56 |
| Isabella Snodgrass | October 14, 1907 | Fairmont, Marion Co., Virginia | March 30, 1848 | 80 |
| Isabella Steward | | | | |
| Isabella VanFossen | WFT Est. 1743-1819 | | WFT Est. 1743-1777 | 34 est. |
| Isabelle Ziemianski | | | | |
| Isadel R. Kincaid | WFT Est. 1883-1976 | Bethlehem Twp, Northampton, Pa. | | 1 est. |
| Isham BURDETT | 1812 | | December 02, 1805 | 29 est. |
| Israel BOONE | June 26, 1756 | Near Chalfont, New Britain Twp, Bucks, PA. | December 31, 1747 | 30 |
| Israel BOONE | August 19, 1782 | Sugar Tree Creek, Davie Co, North Carolina | | 23 |
| Israel Boston | January 20, 1949 | Steinville, Ohio | July 27, 1890 | 87 |
| Israel Kehley | January 14, 1907 | | WFT Est. 1869-1898 | 78 |
| Israel Muffly | 1893 | | | 93 est. |