| Name | Relationship with Elena Brown | Civil | Canon |
| SEASE, EVE MARGARET | Wife of the 7th great-granduncle | | |
| Seehorn, Caroline | Wife of the 1st cousin 6 times removed | | |
| Seigler, Nancy | Wife of the 1st cousin 8 times removed | | |
| Sellers | Husband of the 2nd cousin 5 times removed | | |
| Seltzer, Susannah | Wife of the 2nd cousin 7 times removed | | |
| Seneker, Jacob Susong | Husband of the 1st cousin 6 times removed | | |
| Husband of the 2nd cousin 6 times removed | | |
| Seral, George | Husband of the 1st cousin 3 times removed | | |
| SETZLER, ELIZABETH CUMMINGS | Wife of the 3rd cousin 6 times removed | | |
| SETZLER, POLLY ANN | Wife of the 3rd cousin 6 times removed | | |
| Sewall, John | Husband of the 12th great-grandmother | | |
| SHAMBLIN, CATHERINE “Kate” ELIZABETH | Wife of the 1st cousin 6 times removed | | |
| SHANNON, SABE R. | Husband of the 1st cousin 5 times removed | | |
| SHANNON, WILLIAM | Husband of the 1st cousin 5 times removed | | |
| SHAVER, SALLY | Wife of the 3rd cousin 5 times removed | | |
| SHEALY, ELLA | Wife of the 3rd cousin 6 times removed | | |
| SHELL, JAMES H. | Husband of the 4th cousin 5 times removed | | |
| Sheppard, Ann | Half 10th great-grandaunt | XIV | 13 |
| Sheppard, John | Half 10th great-granduncle | XIV | 13 |
| Sheppard, Major Robert | Husband of the 11th great-grandmother | | |
| SHERRILL, JOSEPH | Husband of the 2nd cousin 7 times removed | | |
| Husband of the 3rd cousin 5 times removed | | |
| Shivers, Beulah MARGARET | Ex-wife of the 4th cousin twice removed | | |
| Ex-wife of the 4th cousin 3 times removed | | |
| Shoopman, Emily K. | Wife of the 3rd great-granduncle | | |
| Shown, EDITH PAULINE | Wife of the 3rd cousin 3 times removed | | |
| Wife of the 3rd cousin 4 times removed | | |
| Siloma ANN | Wife of the 1st cousin 6 times removed | | |
| Wife of the 2nd cousin 8 times removed | | |
| Wife of the 4th cousin 4 times removed | | |
| SIMPSON, ANN REBECCA | 3rd cousin 5 times removed | XIII | 9 |
| SIMPSON, CATHERINE CHESTER | 3rd cousin 5 times removed | XIII | 9 |
| SIMPSON, FRANCIS W. | Husband of the 2nd cousin 6 times removed | | |
| SIMPSON, JAMES FRANCIS | 3rd cousin 5 times removed | XIII | 9 |
| SIMPSON, JOHN BLAIR | 3rd cousin 5 times removed | XIII | 9 |
| SIMPSON, JOHN BLAIR | 3rd cousin 5 times removed | XIII | 9 |
| SIMPSON, JOHN W. | Husband of the 2nd cousin 6 times removed | | |
| SIMPSON, LETITIA | 3rd cousin 5 times removed | XIII | 9 |
| SIMPSON, MARY ELIZA | 3rd cousin 5 times removed | XIII | 9 |
| Sinclaire, Phalby Diez | Wife of the 4th great-granduncle | | |
| Wife of the 5th great-granduncle | | |
| SINGLETON, ALEXANDER | Husband of the 4th cousin 5 times removed | | |
| Sipe, Mary Elizabeth | Wife of the 1st cousin 3 times removed | | |
| Sir | 25th great-grandfather | XXVII | 27 |
| Sir | 24th great-grandfather | XXVI | 26 |
| Sir | Husband of the 23rd great-grandaunt | | |
| Skinner, Nathaniel | Husband of the 2nd cousin 3 times removed | | |
| SLIGH | Wife of the 2nd cousin 7 times removed | | |
| SLIGH, POLLY | Wife of the 2nd cousin 7 times removed | | |
| SLIGH, SOLOMON | Husband of the 1st cousin 8 times removed | | |