| Name | Relationship with Natalie Seiwell | Civil | Canon |
| Sherk, Joseph Trussel | 10th great-grandfather | XII | 12 |
| Sherk, Peter Trussel | 10th great-granduncle | XIV | 13 |
| Sherk, Ulrich Trussel | 10th great-granduncle | XIV | 13 |
| Sherwood, Elizabeth | 15th great-grandmother | XVII | 17 |
| 16th great-grandmother | XVIII | 18 |
| Sherwood, John | 16th great-grandfather | XVIII | 18 |
| 17th great-grandfather | XIX | 19 |
| Shipley, Mary A. | 3rd great-grandmother | V | 5 |
| Shirk, Anna Burkhard | 8th great-grandmother | X | 10 |
| Wife of the 4th cousin 8 times removed | | |
| Shirk, Casper Burkhard | 8th great-granduncle | XII | 11 |
| Shirk, Joseph Burkhard | 8th great-granduncle | XII | 11 |
| Sibton, Margaret | 25th great-grandmother | XXVII | 27 |
| Siegfried, Abraham Daniel Spengler | Husband of the 5th cousin 3 times removed | | |
| Siegfried, Celia Elizabeth Pennepacker | 6th cousin twice removed | XVI | 9 |
| Simpson, Ann Donelly | 5th cousin 3 times removed | XV | 9 |
| Simpson, Ann Vanderslice | 4th cousin 4 times removed | XIV | 9 |
| Simpson, Charles V. Herren | 6th cousin twice removed | XVI | 9 |
| Simpson, Hannah Vanderslice | 4th cousin 4 times removed | XIV | 9 |
| Simpson, Henry Vanderslice | 4th cousin 4 times removed | XIV | 9 |
| Simpson, Henry Vanderslice Haas | 5th cousin 3 times removed | XV | 9 |
| Simpson, Jeremiah | Husband of the 3rd cousin 5 times removed | | |
| Simpson, Jeremiah Vanderslice | 4th cousin 4 times removed | XIV | 9 |
| Simpson, Jesse Michael Monroe Vanderslice | 4th cousin 4 times removed | XIV | 9 |
| Simpson, John Vanderslice | 4th cousin 4 times removed | XIV | 9 |
| Simpson, Mary Anna Herren | 6th cousin twice removed | XVI | 9 |
| Simpson, Mary Vanderslice | 4th cousin 4 times removed | XIV | 9 |
| Simpson, Mary Vanderslice Donelly | 5th cousin 3 times removed | XV | 9 |
| Simpson, Rachel Vanderslice | 4th cousin 4 times removed | XIV | 9 |
| Simpson, Sarah Ann Haas Herren | 6th cousin twice removed | XVI | 9 |
| Simpson, Sarah Cook Vanderslice | 4th cousin 4 times removed | XIV | 9 |
| Sinclair, Agnes | 16th great-grandmother | XVIII | 18 |
| Sinclair, Annabel Dunbar | 21st great-grandmother | XXIII | 23 |
| 1st cousin 22 times removed | XXVI | 24 |
| 23rd great-grandaunt | XXVII | 26 |
| 1st cousin 24 times removed | XXVIII | 26 |
| 1st cousin 25 times removed | XXIX | 27 |
| 3rd cousin 21 times removed | XXIX | 25 |
| 1st cousin 26 times removed | XXX | 28 |
| 3rd cousin 25 times removed | XXXIII | 29 |
| 3rd cousin 26 times removed | XXXIV | 30 |
| 3rd cousin 27 times removed | XXXV | 31 |
| 6th cousin 21 times removed | XXXV | 28 |
| 6th cousin 22 times removed | XXXVI | 29 |
| 6th cousin 23 times removed | XXXVII | 30 |
| 6th cousin 24 times removed | XXXVIII | 31 |
| 6th cousin 25 times removed | XXXIX | 32 |
| 6th cousin 26 times removed | XL | 33 |
| 6th cousin 27 times removed | XLI | 34 |
| Sinclair, Beatrix Haliburton | 19th great-grandmother | XXI | 21 |