| Name | Spouse | Marriage date | Marriage location |
|---|
| Ada G. Holbrook | | | |
| Adam Gus Holbrook | Miller, Kate | | |
| Addie Elizabeth Holbrook | Howard, John Tilden | August 27, 1913 | Floyd Co., Kentucky |
| Alexander Campbell Holbrook | | | |
| Alfred Holbrook | | | |
| Amanda Holbrook | | | |
| Amelia Holbrook | Eller, William | December 26, 1860 | Wilkes Co., North Carolina |
| Anna Lee Holbrook | | | |
| Arby S. Holbrook | | | |
| Assennath male or female Holbrook | | | |
| Augusta Greer Holbrook | McDade, John Longacre | | |
| B.M. Holbrook | | | |
| Ballard Holbrook | Martin, Thelma | Private | |
| Benjamin Holbrook | Jenkins, Nancy | March 02, 1820 | Floyd Co., Kentucky |
| Benjamin Holbrook | | | |
| Benjamin M. Holbrook | Spradlin, Rhoda Bays | March 16, 1850 | Morgan Co., Kentucky |
| Bennie Holbrook | | | |
| Bernard Holbrook | Barnett, Elsie | Private | |
| Bernice Holbrook | | | |
| Betty Lou Holbrook | | | |
| Braddock Holbrook | Jordan, Judy | | |
| Brenda Holbrook | | | |
| Brenda Sue Holbrook | | | |
| Brian Holbrook | | | |
| Cam S. Holbrook | Flannery, Mary L. | August 21, 1909 | Johnson Co., Kentucky |
| Camiel M. Holbrook | Miller, Nora | May 03, 1912 | Home of Adam G. Holbrook, Floyd Co., Kentucky |
| Campbell R. Holbrook | Holbrook, Susan Ann | May 08, 1856 | Johnson Co., Kentucky |
| Caninel H. Holbrook | | | |
| Carpenter Holbrook | Risner, Nancy "Nannie" | Private | |
| Catherine Holbrook | Billings, William Wilburn | | |
| Cecily Holbrook | Taylor, Thomas P. | | |
| Charles Holbrook | Dora | | |
| Charlotte Holbrook | | | |
| Claris Holbrook | Burton, Henry | Private | |
| Claude G. Holbrook | Ritchie, Curalene | Private | |
| Claudette Holbrook | | | |
| Colby Holbrook | Celia | | |
| Colby Jr. Holbrook | Nancy | | |
| Columbus T. Holbrook | | | |
| Covey Holbrook | Stollard, Francis E. | December 30, 1863 | Wise Co., Virginia |
| Crosby E. Holbrook | | | |
| Cylus Holbrook | | | |
| Cynthia Holbrook | | | |
| Damon Holbrook | | | |
| David Gersham Holbrook | | | |
| David Henderson Holbrook | Bills, Sarah Summers | | |
| David Holbrook | | | |
| David Holbrook | Crouse, Margaret | | |
| David J. Holbrook | Prince, Hannah Paulina | | |
| David Jr. Holbrook | Judy | Private | |
