| Name | Birth date | Birth location | Marriage date | Death date | Death location |
|---|
| Elizabeth Killingsworth Middleton | November 08, 1839 | | November 08, 1857 | March 01, 1923 | Toledo, Ohio buried in Forstoria, Ohio |
| Elizabeth Kilmlenworth Middleton | 1806 | | August 19, 1921 | | buried near Prescott, Iowa |
| Ella Frances Middleton | November 24, 1857 | | November 22, 1881 | | |
| Ella May Middleton | July 15, 1867 | | October 28, 1886 | | |
| Elmer Palestine Middleton | June 18, 1870 | | | August 24, 1870 | |
| Elva Middleton | April 06, 1866 | | April 11, 1882 | | |
| Erma Lois Middleton | July 02, 1909 | | | | |
| Ethel Middleton | October 25, 1890 | | March 05, 1919 | | |
| Euphemia Aboline (Abbie) Middleton | August 06, 1857 | Hartford, Iowa | November 12, 1876 | May 06, 1932 | on a Friday, in Detroit |
| Eutoca May Middleton | March 02, 1869 | | December 12, 1894 | | |
| Eva Iona Middleton | August 16, 1875 | Missouri | | March 1897 | Humeston, Iowa |
| Everett Middleton | | | | | |
| Florence Middleton | July 30, 1912 | | | | |
| Floyd Middleton | | | | | |
| Floyd Earl Middleton | November 01, 1888 | | January 31, 1923 | | |
| Forest Lee Middleton | April 05, 1920 | | | | |
| Francis Ellen Middleton | August 20, 1923 | | | | |
| Francis Lorain Middleton | February 14, 1867 | Kirksville, Missouri | June 20, 1892 | | |
| Francis Lorin Taylor Middleton | February 10, 1908 | Unionville, Missouri | | | |
| Francis M. Middleton | | | | | died in infancy |
| Francis Ozias Middleton | March 10, 1879 | Savannah, Missouri | April 27, 1904 | | |
| Fred Grant Middleton | February 16, 1885 | Sugar Grove, Indiana | September 19, 1906 | | |
| Genevieve Middleton | | | | | |
| Gertrude Middleton | | | | | |
| Glen Middleton | | | | | |
| Harrold Middleton | | | | | |
| Harvey Middleton | | | | | |
| Hattie May Middleton | October 12, 1880 | | June 08, 1897 | | |
| Helen Jacquelin Middleton | November 20, 1928 | | | | |
| Helen Vivan Middleton | February 08, 1914 | | | | |
| Henrietta E. Middleton | | | | | died in infancy |
| Henry Middleton | 1717 | | | June 13, 1784 | |
| Henry Middleton | 1770 | | | 1846 | |
| Henry D. Middleton | February 28, 1831 | Stillwell, LaPorte County, Indiana | | February 14, 1839 | LaPorte County, Indiana |
| Herbert Middleton | | | | | |
| Homer Middleton | December 19, 1866 | | | October 02, 1867 | |
| Howard Middleton | | | | | |
| Howard Middleton | February 07, 1887 | | August 1912 | June 29, 1931 | |
| Howard Middleton | July 05, 1917 | | | | |
| Ina Loreta Middleton | August 29, 1866 | | November 13, 1889 | | |
| Iva Middleton | November 07, 1894 | | | | |
| Jack Allen Middleton | October 05, 1941 | | March 29, 1959 | | |
| Jacob (Jake) Middleton | July 04, 1855 | | | | |
| James Middleton | 1750 | | 1775 | 1798 | Sussex County, Delaware |
| James Middleton | 1797 | | | 1804 | |
| James B. Middleton | March 12, 1804 | Sussex, Delaware | Abt 1845 | March 05, 1870 | |
| Jennie Middleton | October 30, 1868 | | | Abt June 1869 | |
| Jennie Jane Middleton | March 19, 1893 | | February 22, 1913 | | |
| Jesse Adams Middleton | June 05, 1895 | | March 04, 1916 | | |
| John Middleton | February 12, 1777 | | | July 17, 1847 | |
